The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2020
Filed:
Feb. 02, 2015
Applicant:
N.v. Nutricia, Zoetermeer, NL;
Inventors:
Assignee:
N.V. NUTRICIA, Zoetermeer, NL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/7068 (2006.01); A61K 31/7072 (2006.01); A61K 31/14 (2006.01); A61K 31/202 (2006.01); A61K 31/355 (2006.01); A61K 31/375 (2006.01); A61K 31/4415 (2006.01); A61K 31/519 (2006.01); A61K 31/683 (2006.01); A61K 31/714 (2006.01); A61K 33/04 (2006.01); A61K 45/06 (2006.01); A61K 31/685 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7068 (2013.01); A61K 31/14 (2013.01); A61K 31/202 (2013.01); A61K 31/355 (2013.01); A61K 31/375 (2013.01); A61K 31/4415 (2013.01); A61K 31/519 (2013.01); A61K 31/683 (2013.01); A61K 31/685 (2013.01); A61K 31/7072 (2013.01); A61K 31/714 (2013.01); A61K 33/04 (2013.01); A61K 45/06 (2013.01);
Abstract
The invention pertains to the use of one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof in the manufacture of a composition for treating, preventing or reducing the risk of occurrence of white matter lesions, white matter hyperintensities (WMH), Leukoaraiosis or periventricular white matter disease in elderly not suffering from a neurodegenerative disorder, preferably non-demented elderly and elderly not suffering from Alzheimer's Disease. It was found that with the compositions according to the invention Nogo-A protein levels could be controlled, particularly suppressed or reduced.