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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10675292 B1

PDFFull Text
Date of Patent:
Jun. 09, 2020

Filed:

Feb. 02, 2015

Method for reducing white matter lesions, white matter hyperintensities (wmh), leukoaraiosis or periventricular white matter disease in elderly

Applicant:

N.v. Nutricia, Zoetermeer, NL;

Inventors:

Nick Van Wijk, Utrecht, NL;

Robert Johan Joseph Hageman, Utrecht, NL;

Mehmet Cansev, Bursa, TR;

Assignee:

N.V. NUTRICIA, Zoetermeer, NL;

Attorney:

Foley & Lardner LLP

Primary Examiner:

Ali Soroush

Assistant Examiner:

Courtney A Brown

Int. Cl.
CPC ...
A61K 31/7068 (2006.01); A61K 31/7072 (2006.01); A61K 31/14 (2006.01); A61K 31/202 (2006.01); A61K 31/355 (2006.01); A61K 31/375 (2006.01); A61K 31/4415 (2006.01); A61K 31/519 (2006.01); A61K 31/683 (2006.01); A61K 31/714 (2006.01); A61K 33/04 (2006.01); A61K 45/06 (2006.01); A61K 31/685 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7068 (2013.01); A61K 31/14 (2013.01); A61K 31/202 (2013.01); A61K 31/355 (2013.01); A61K 31/375 (2013.01); A61K 31/4415 (2013.01); A61K 31/519 (2013.01); A61K 31/683 (2013.01); A61K 31/685 (2013.01); A61K 31/7072 (2013.01); A61K 31/714 (2013.01); A61K 33/04 (2013.01); A61K 45/06 (2013.01);
Abstract

The invention pertains to the use of one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof in the manufacture of a composition for treating, preventing or reducing the risk of occurrence of white matter lesions, white matter hyperintensities (WMH), Leukoaraiosis or periventricular white matter disease in elderly not suffering from a neurodegenerative disorder, preferably non-demented elderly and elderly not suffering from Alzheimer's Disease. It was found that with the compositions according to the invention Nogo-A protein levels could be controlled, particularly suppressed or reduced.

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Van Wijk, Nick. (2020). Method for reducing white matter lesions, white matter hyperintensities (wmh), leukoaraiosis or periventricular white matter disease in elderly (U.S. Patent No. 10675292). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10675292

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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