The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Oct. 01, 2013
Molecular Health Gmbh, Heidelberg, DE;
Alexander Zien, Heidelberg, DE;
David B. Jackson, Heidelberg, DE;
Martin Stein, Mannheim, DE;
Guillaume Taglang, Heidelberg, DE;
Stephan Brock, Weinheim, DE;
Alexander Picker, Heidelberg, DE;
Theodoros Soldatos, Heidelberg, DE;
Bernhard Sulzer, Heidelberg, DE;
Molecular Health GmbH, Heidelberg, DE;
Abstract
The present disclosure relates to systems and methods for bioinformatics and data processing. In particular, in a first aspect, the present disclosure relates to methods and systems for generating a personalized treatment guideline for a patient and for selecting a treatment for a patient. In another aspect, the present disclosure relates to methods and systems for selecting patients for a clinical trial of a treatment. The invention resolves cases in which patients have more than one 'actionable' aberration by combining the patient-specific molecular information and the treatment-specific molecular information further with a clinico-molecular disease model, specifically a scoring of genes and/or proteins that represents several aspects of their involvement into the disease. In this way, treatments and patients can be prioritized that are most likely to impact or impacted by the disease mechanism, respectively.