The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Feb. 04, 2016
Ad Pharmaceutical Co., Inc., Science City, CN;
Baiyong Li, Guangdong, CN;
Zhongmin Wang, Guangdong, CN;
Yu Xia, Guangdong, CN;
Peng Zhang, Guangdong, CN;
Wuxian Ren, Guangdong, CN;
Jinan Jiao, Guangdong, CN;
Yuanyuan Xu, Guangdong, CN;
Dongsheng Dai, Guangdong, CN;
AD Pharmaceutical Co., Inc., Science, Guangzhou Development Zone, CN;
Abstract
The present invention belongs to the field of immunology and molecular biology, which relates to an anti-PCSK9 antibody, the pharmaceutical composition and method of use thereof. In particular, the present invention relates to the monoclonal antibody, which can bind PCSK9 specifically, block association of PCSK9 with LDLR, upregulate the amount of LDLR on cell surface, heighten the metabolism of LDL cholesterol and/or triglycerides, and prevent/treat cardiovascular diseases caused by hypercholesterolemia.