The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Apr. 09, 2019
Applicant:
Children's Medical Center Corporation, Boston, MA (US);
Inventor:
Randolph Watnick, Newton, MA (US);
Assignee:
Children's Medical Center Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); G01N 33/574 (2006.01); C07K 14/475 (2006.01); A61K 45/06 (2006.01); A61K 38/17 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/574 (2013.01); A61K 38/1709 (2013.01); A61K 45/06 (2013.01); C07K 14/475 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); G01N 2800/56 (2013.01);
Abstract
The invention relates to isolated peptides and chimeric polypeptides derived from Saposin A that have anti-angiogenic activity. These peptides are small, consisting essentially of at least 10 consecutive amino acid residues from the 31st-50amino acid residue of Saposin A. The invention also relates to the use of these isolated peptides and chimeric polypeptides in compositions for the treatment, prevention, and inhibition of angiogenesis-related diseases and disorders such as cancer and cancer metastasis.