The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Feb. 25, 2016
Drk-blutspendedienst Baden-wuerttemberg-hessen Ggmbh, Frankfurt am Main, DE;
Johann Wolfgang Goethe-universität Frankfurt AM Main, Frankfurt am Main, DE;
Halvard Boenig, Frankfurt, DE;
Christof Geisen, Cologne, DE;
Eliza Justyna Wiercinska, Zwingenberg, DE;
Nikolas Ryschka, Frankfurt am Main, DE;
DRK-Blutspendedienst Baden-Wuerttemberg-Hessen gGmgH, Frankfurt am Main, DE;
Johann Wolfgang Goethe-Universitaet Frankfurt am Main, Frankfurt am Main, DE;
Abstract
The present invention provides a cellular system for the detection of the presence of one or more antibody species in sample, preferably a serum or plasma sample. The method is in particular useful for the analysis of patients who have been sensitized against blood group antigens expressed on erythrocytes, platelets or granulocytes. The system uses fluorescence labeled cells specific for each antigen and hence, for each antibody species. Provided are the methods, system and diagnostic kits for performing the methods of the invention. In addition, the present invention discloses a method for removing antibodies from a sample such as a serum sample. Such a method is useful for absorbing antibodies from poly-agglutinating sera.