The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2020

Filed:

Sep. 19, 2014
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Daniel Irimia, Charlestown, MA (US);

Caroline Jones, Charlestown, MA (US);

Anh Hoang, Brighton, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 15/14 (2006.01); B01L 3/00 (2006.01); G01N 15/10 (2006.01); G01N 15/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5029 (2013.01); B01L 3/5027 (2013.01); G01N 15/1463 (2013.01); G01N 15/1484 (2013.01); G01N 33/5047 (2013.01); B01L 2200/0668 (2013.01); B01L 2300/0803 (2013.01); B01L 2300/0867 (2013.01); B01L 2400/0472 (2013.01); B01L 2400/086 (2013.01); G01N 2015/0065 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1075 (2013.01); G01N 2015/1486 (2013.01);
Abstract

A device includes an input chamber, an attractant chamber, a migration channel arranged in fluid communication between an outlet of the input chamber and inlet of the attractant chamber, a baffle arranged in fluid communication between the outlet of the input chamber and the migration channel or within the migration channel, and an exit channel in fluid communication with the migration channel at a point beyond the baffle and before the migration channel enters the inlet of the attractant chamber. The baffle is configured to inhibit movement of a first type of cell through the baffle to a greater extent than the baffle inhibits movement of a second type of cell through the baffle.


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