The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2020

Filed:

Feb. 26, 2019
Applicant:

Clinical Micro Sensors, Inc., Carlsbad, CA (US);

Inventors:

Lisa Lynn Freeman-Cook, Carlsbad, CA (US);

Christine J. Shaw, San Diego, CA (US);

Milena Iacobelli Martinez, Vista, CA (US);

Anna Maria Al-Khouri, San Diego, CA (US);

Bradley Adam Brown, San Marcos, CA (US);

John Jay Harvey, San Marcos, CA (US);

Assignee:

Clinical Micro Sensors, Inc., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12Q 1/689 (2018.01); C12Q 1/686 (2018.01); C12Q 1/6853 (2018.01); C12Q 1/6895 (2018.01); G01N 27/327 (2006.01); G01N 27/48 (2006.01); G16H 15/00 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/689 (2013.01); B01L 3/5023 (2013.01); B01L 3/5027 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6853 (2013.01); C12Q 1/6895 (2013.01); G01N 27/3277 (2013.01); G01N 27/48 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0819 (2013.01); C12Q 2600/16 (2013.01); G16H 15/00 (2018.01);
Abstract

The present disclosure relates to methods and devices for amplifying a plurality of targets in a single PCR run while distinguishing between clinically relevant amplification and amplification from other sources such as from background contamination. The methods and devices further enable discrimination between gram-positive, gram-negative and fungal infections as wells as identify antimicrobial resistance genes. When applying the methods and devices of the invention, the species or genus of an infection(s), and genus of a fungal co-infection(s) or category of bacterial (gram-positive or negative) co-infection(s) are identified. Species identification of co-infections can also be achieved. Further, when applying the methods and devices of the invention, organisms which are likely to be contaminating organisms from a blood draw are identified.


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