The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Feb. 27, 2019
Applicant:
Blueprint Medicines Corporation, Cambridge, MA (US);
Inventors:
Ethan G. Cerami, Winchester, MA (US);
Christoph Lengauer, Cambridge, MA (US);
Nicolas Stransky, Charlestown, MA (US);
Assignee:
Blueprint Medicines Corporation, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C07H 21/04 (2006.01); C12Q 1/6886 (2018.01); A61K 31/7088 (2006.01); C12N 15/113 (2010.01); C12Q 1/6806 (2018.01); C12Q 1/6813 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 31/7088 (2013.01); C12N 15/1137 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6813 (2013.01); C12Q 2600/156 (2013.01);
Abstract
The invention provides PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha) gene fusions, and fragments of those gene fusions. The invention further provides methods of diagnosing and treating diseases or disorders associated with PIK3CA fusions, such as conditions mediated by PIK3CA aberrant expression or activity, or overexpression of PIK3CA.