The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Apr. 22, 2019
Applicant:
Promega Corporation, Madison, WI (US);
Inventors:
Anton Shakhmin, Grover Beach, CA (US);
Thomas Kirkland, Atascadero, CA (US);
Joel Walker, San Luis Obispo, CA (US);
Thomas Machleidt, Madison, WI (US);
Mary Hall, Waunakee, WI (US);
Keith V. Wood, Mount Horeb, WI (US);
Assignee:
PROMEGA CORPORATION, Madison, WI (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C12Q 1/66 (2006.01); C07D 519/00 (2006.01); A61K 49/00 (2006.01); G01N 33/58 (2006.01); H04N 1/60 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/66 (2013.01); A61K 49/0013 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01); G01N 33/581 (2013.01); H04N 1/6041 (2013.01); G01N 2333/90241 (2013.01);
Abstract
Described are substituted imidazo[1,2-a]pyrazine compounds, which are coelenterazine analogues, kits comprising the compounds, and methods of using the compounds for the detection of luminescence in luciferase-based assays. Also described are methods from making the compounds, such as a method using aminopyrazine acetophosphonates as synthesis intermediates.