The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Feb. 07, 2019
Applicant:
Immunobiology Limited, Cambridge, GB;
Inventors:
Camilo Colaco, Cambridge, GB;
Ian McEntee, Salisbury, GB;
Assignee:
Immunobiology Limited, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); A61K 39/00 (2006.01); A61K 38/17 (2006.01); A61K 39/04 (2006.01); A61K 39/08 (2006.01); A61K 39/09 (2006.01); A61K 39/095 (2006.01);
U.S. Cl.
CPC ...
C12P 21/00 (2013.01); A61K 38/1709 (2013.01); A61K 39/0002 (2013.01); A61K 39/0011 (2013.01); A61K 39/04 (2013.01); A61K 39/08 (2013.01); A61K 39/092 (2013.01); A61K 39/095 (2013.01); Y02A 50/403 (2018.01); Y02A 50/478 (2018.01); Y02A 50/48 (2018.01);
Abstract
The present invention relates to methods for the production of heat shock protein complexes for use in vaccine compositions. In particular, there is provided a method for increasing the level and immunogenicity of heat shock protein complexes produced in cells by subjecting the cells to specific stress inducing stimuli. The invention further extends to the use of heat shock protein complexes produced according to the methods of the invention in the preparation of vaccine compositions for the prevention and treatment of infectious diseases and cancerous conditions.