The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2020

Filed:

Jul. 02, 2015
Applicant:

Genomatica, Inc., California, CA (US);

Inventors:

Stephanie J. Culler, San Diego, CA (US);

Mark J. Burk, San Diego, CA (US);

Robin E. Osterhout, San Diego, CA (US);

Priti Pharkya, San Diego, CA (US);

Assignee:

GENOMATICA, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 1/20 (2006.01); C12N 9/00 (2006.01); C12N 9/02 (2006.01); C12N 9/88 (2006.01); C12N 9/90 (2006.01); C07H 21/04 (2006.01); C12P 7/04 (2006.01); C12N 15/52 (2006.01); C12P 5/02 (2006.01); C12P 7/40 (2006.01); C12N 9/04 (2006.01);
U.S. Cl.
CPC ...
C12P 7/04 (2013.01); C12N 9/0006 (2013.01); C12N 9/88 (2013.01); C12N 9/90 (2013.01); C12N 15/52 (2013.01); C12P 5/026 (2013.01); C12P 7/40 (2013.01); Y02E 50/343 (2013.01);
Abstract

The invention provides a non-naturally occurring microbial organism having a butadiene, crotyl alcohol, 2,4-pentadienoate, 3-buten-2-ol, or 3-buten-1-ol, pathway. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in a pathway. The invention additionally provides a method for producing butadiene, crotyl alcohol, 2,4-pentadienoate, 3-buten-2-ol, or 3-buten-1-ol. The method can include culturing a butadiene, crotyl alcohol, 2,4-pentadienoate, 3-buten-2-ol, or 3-buten-1-ol-producing microbial organism, where the microbial organism expresses at least one exogenous nucleic acid encoding a pathway enzyme in a sufficient amount, and under conditions and for a sufficient period of time to produce butadiene, crotyl alcohol, 2,4-pentadienoate, 3-buten-2-ol, or 3-buten-1-ol.


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