The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2020

Filed:

Jul. 30, 2014
Applicant:

Lonza Biologics Plc, Slough, GB;

Inventors:

Marc Feary, Newmarket, GB;

James Rance, Thame, GB;

Robert Young, London, GB;

Elizabeth C. Sayer, Redhill, GB;

Christopher M. Smales, Chartham, GB;

Assignee:

LONZA BIOLOGICS PLC., Slough, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12P 21/00 (2006.01); C12N 15/11 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C07K 16/00 (2013.01); C12N 15/111 (2013.01); C12P 21/00 (2013.01); C12N 2310/141 (2013.01); C12N 2330/51 (2013.01);
Abstract

Methods for generating mammalian cells characterized by an increased concentration of at least one of miR-15, miR-16, and miR-34 for producing proteins at an industrial scale are provided. Methods for using the mammalian cells, in particular for the production of proteins of interest, are also provided.


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