The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Dec. 10, 2018
Jiangnan University, Wuxi, CN;
Max Planck Institute of Colloids and Interfaces, Potsdam, DE;
Jiangnan University, Jiangsu, Wuxi, CN;
Abstract
The disclosure discloses a preparation method of outer core octasaccharide oflipopolysaccharide, and belongs to the field of carbohydrate chemistry. The structure of the outer core octasaccharide ofis (α-D-Glc-(1-3)-α-D-Glc-(1-4)-β-D-Gal-(1-7)-D-α-D-Hep[α-D-Glc-(1-6)-α-D-Glc-(1-6)-α-D-Glc-(1-2)-D-α-D-Hep]-Linker. The structure consists of three monosaccharides: glucose, galactose and heptose. It contains five α-glycosidic bonds of glucose, one β-glycosidic bond of galactose and two α-glycosidic bonds of heptose. The disclosure prepares the octasaccharide by the synergistic action of remote neighboring group participation effect, solvent effect, temperature effect, additives and leaving groups. The reducing end of the octasaccharide may also be linked with a linker for future attachment to the protein to form a glycoconjugate for immunological studies.