The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Feb. 13, 2018
Applicants:
Agensys, Inc., Santa Monica, CA (US);
Seattle Genetics, Inc., Bothell, WA (US);
Inventors:
Robert Kendall Morrison, Santa Monica, CA (US);
Zili An, Santa Monica, CA (US);
Karen Jane Meyrick Morrison, Santa Monica, CA (US);
Josh Snyder, Santa Monica, CA (US);
Xiao-Chi Jia, Los Angeles, CA (US);
Assignees:
AGENSYS, INC., Santa Monica, CA (US);
SEATTLE GENETICS, INC., Bothell, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/30 (2006.01); C07K 16/18 (2006.01); A61K 45/06 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 45/06 (2013.01); A61K 47/6803 (2017.08); A61K 47/6811 (2017.08); A61K 47/6813 (2017.08); A61K 47/6817 (2017.08); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); A61K 47/6855 (2017.08); A61K 47/6857 (2017.08); A61K 47/6859 (2017.08); A61K 47/6861 (2017.08); A61K 47/6865 (2017.08); A61P 35/00 (2018.01); C07K 16/18 (2013.01); C07K 16/3015 (2013.01); C07K 16/3023 (2013.01); C07K 16/3038 (2013.01); C07K 16/3053 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/56 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01);
Abstract
Antibody drug conjugates (ADC's) that bind to 158P1D7 protein and variants thereof are described herein. 158P1D7 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in glioblastoma, lung cancer, bladder cancer, and breast cancer. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.