The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Jan. 07, 2019
Applicant:
New York University, New York, NY (US);
Inventors:
Victor J. Torres, New York, NY (US);
Francis Alonzo, III, Chicago, IL (US);
Assignee:
New York University, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/12 (2006.01); A61K 39/40 (2006.01); A61K 39/085 (2006.01); A61K 31/7088 (2006.01); A61K 31/724 (2006.01); G01N 33/50 (2006.01); A61K 38/16 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1271 (2013.01); A61K 31/7088 (2013.01); A61K 31/724 (2013.01); A61K 38/164 (2013.01); A61K 39/085 (2013.01); A61K 39/40 (2013.01); C07K 16/12 (2013.01); G01N 33/5014 (2013.01); G01N 33/5047 (2013.01); G01N 33/56938 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/76 (2013.01); G01N 2333/31 (2013.01); G01N 2469/10 (2013.01); G01N 2500/10 (2013.01); G01N 2800/56 (2013.01);
Abstract
The present invention relates to methods and compositions for preventing and treatingin a subject. Therapeutic compositions of the present invention comprise leukocidin E and/or D proteins or polypeptides and anti-leukocidin E and/or D antibodies. The invention further relates to methods of identifying inhibitors of LukE/D cytotoxicity and inhibitors of LukE/D-leukocyte binding.