The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2020

Filed:

Jun. 26, 2019
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Upender Velaparthi, Princeton Junction, NJ (US);

Louis S. Chupak, Old Saybrook, CT (US);

Chetan Padmakar Darne, Ewing, NJ (US);

Min Ding, Stow, MA (US);

Robert G. Gentles, Killingworth, CT (US);

Yazhong Huang, Wallingford, CT (US);

Manjunatha Narayana Rao Kamble, Bangalore, IN;

Scott W. Martin, Middletown, CT (US);

Raju Mannoori, Bangalore, IN;

Ivar M. McDonald, Woodstock, CT (US);

Richard E. Olson, Cambridge, MA (US);

Hasibur Rahaman, Bangalore, IN;

Prasada Rao Jalagam, Bangalore, IN;

Saumya Roy, Bangalore, IN;

Gopikishan Tonukunuru, Bangalore, IN;

Sivasudar Velaiah, Hosur, IN;

Jayakumar Sankara Warrier, Bangalore, IN;

Xiaofan Zheng, Cheshire, CT (US);

John S. Tokarski, Princeton, NJ (US);

Bireshwar Dasgupta, Doylestown, PA (US);

Kotha Rathnakar Reddy, Warangal West, IN;

Thiruvenkadam Raja, Hosur, IN;

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07D 487/04 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01);
Abstract

Disclosed are compounds of Formula (I): or a salt thereof, wherein: R, R, R, R, R, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGKα) and diacylglycerol kinase zeta (DGKζ), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.


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