The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Aug. 09, 2017
Applicant:
Axxam S.p.a., Bresso (MI), IT;
Inventors:
Paolo Pevarello, Bresso, IT;
Adolfo Prandi, Bresso, IT;
Assignee:
Axxam S.P.A., Bresso (MI), IT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/00 (2006.01); C07D 417/02 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01); A61P 27/02 (2006.01); A61P 21/00 (2006.01); A61P 25/00 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
C07D 417/02 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01); A61P 21/00 (2018.01); A61P 25/00 (2018.01); A61P 27/02 (2018.01); A61P 29/00 (2018.01);
Abstract
The present invention relates to novel substituted phenoxy- and benzyloxy-piperidine compounds of formula (I) having P2X7 receptor (P2X7) antagonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans.