The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
May. 30, 2017
Applicant:
Toxinvent Oü, Tartu, EE;
Inventors:
Ain Uustare, Tartu, EE;
Ivan Ogibalov, Tartu, EE;
Olga T{hacek over (s)}ubrik, Tartu, EE;
Andrus Tasa, Tartu, EE;
Uno Mäeorg, Tartu, EE;
Ago Rinken, Tartu, EE;
Assignee:
Toxinvent Ou, Tartu, EE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); A61K 47/68 (2017.01); A61K 31/424 (2006.01); C07H 15/252 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6809 (2017.08); A61K 31/424 (2013.01); C07D 498/04 (2013.01); C07H 15/252 (2013.01);
Abstract
The present invention relates to novel anthracycline derivatives comprising two oxazolidine cycles and the preparation of said anthracycline derivatives. Furthermore, antibody-drug conjugates (ADCs) comprising the novel anthracycline derivatives and the use of such ADCs in the prevention and treatment of cancer are disclosed.