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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10668134 B1

PDFFull Text
Expired
Date of Patent:
Jun. 02, 2020

Filed:

Mar. 31, 2017

Dental pretreatment material and dental tissue regeneration kit

Applicant:

National Center for Geriatrics and Gerontology, Aichi, JP;

Inventors:

Misako Nakashima, Aichi, JP;

Koichiro Iohara, Aichi, JP;

Hideto Watanabe, Aichi, JP;

Assignee:

NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY, Aichi, JP;

Attorney:

Alston & Bird LLP

Primary Examiner:

Sean C Barron

Int. Cl.
CPC ...
A61K 38/48 (2006.01); A61P 1/02 (2006.01); A61K 9/51 (2006.01); A61L 27/38 (2006.01); A61L 27/54 (2006.01); A61L 27/50 (2006.01); A61K 6/00 (2020.01); A61K 6/80 (2020.01);
U.S. Cl.
CPC ...
A61K 38/4826 (2013.01); A61K 6/00 (2013.01); A61K 6/80 (2020.01); A61K 9/51 (2013.01); A61K 38/48 (2013.01); A61L 27/3804 (2013.01); A61L 27/3865 (2013.01); A61L 27/50 (2013.01); A61L 27/54 (2013.01); A61P 1/02 (2018.01); C12Y 304/21004 (2013.01);
Abstract

Provided is a dental pretreatment material for dental tissue regeneration by use of dental pulp stem cells, particularly a dental pretreatment material effectively enabling dental tissue regeneration even by use of dental pulp stem cells of middle-aged or older individuals. The dental pretreatment material is characterized by comprising a serine protease, specifically trypsin. The dental pretreatment material comprising trypsin is used as an injection into a root canal before a root canal filling material comprising dental pulp stem cells and an extracellular matrix is inserted into the root canal as an attempt to regenerate a dental pulp and a dentin. The root canal filling material includes an ALK5 inhibitor, a CCR3 antagonist, or a CCL11 neutralizing antibody.

Find Patent Forward Citations

Nakashima, Misako. (2020). Dental pretreatment material and dental tissue regeneration kit (U.S. Patent No. 10668134). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10668134

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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