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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10668087 B1

PDFFull Text
Date of Patent:
Jun. 02, 2020

Filed:

Oct. 11, 2018

Methods for inhibiting muscle atrophy

Applicants:

University of Iowa Research Foundation, Iowa City, IA (US);

The United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Christopher M. Adams, Iowa City, IA (US);

Steven D. Kunkel, West Richland, WA (US);

Michael Welsh, Riverside, IA (US);

Assignees:

UNIVERSITY OF IOWA RESEARCH FOUNDATION, Iowa City, IA (US);

THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, Washington, DC (US);

Attorney:

Heslin Rothenberg Farley & Mesiti P.C.

Primary Examiner:

Dennis Heyer

Int. Cl.
CPC ...
A61K 31/353 (2006.01); G01N 33/50 (2006.01); A61K 31/473 (2006.01); A61K 31/565 (2006.01); A61K 31/407 (2006.01); A61K 31/58 (2006.01); A61K 31/435 (2006.01); A61K 31/436 (2006.01); A61K 31/215 (2006.01); A61K 31/352 (2006.01); A61K 31/36 (2006.01); A61K 31/382 (2006.01); A61K 31/404 (2006.01); A61K 31/4164 (2006.01); A61K 31/4166 (2006.01); A61K 31/4355 (2006.01); A61K 31/4365 (2006.01); A61K 31/437 (2006.01); A61K 31/4375 (2006.01); A61K 31/438 (2006.01); A61K 31/4706 (2006.01); A61K 31/56 (2006.01); C12Q 1/6809 (2018.01);
U.S. Cl.
CPC ...
A61K 31/58 (2013.01); A61K 31/215 (2013.01); A61K 31/352 (2013.01); A61K 31/353 (2013.01); A61K 31/36 (2013.01); A61K 31/382 (2013.01); A61K 31/404 (2013.01); A61K 31/407 (2013.01); A61K 31/4164 (2013.01); A61K 31/4166 (2013.01); A61K 31/435 (2013.01); A61K 31/436 (2013.01); A61K 31/437 (2013.01); A61K 31/438 (2013.01); A61K 31/4355 (2013.01); A61K 31/4365 (2013.01); A61K 31/4375 (2013.01); A61K 31/473 (2013.01); A61K 31/4706 (2013.01); A61K 31/56 (2013.01); A61K 31/565 (2013.01); C12Q 1/6809 (2013.01); G01N 33/5023 (2013.01); C12Q 2600/136 (2013.01); G01N 2800/10 (2013.01); G01N 2800/52 (2013.01);
Abstract

In one aspect, the invention relates to methods for treating muscle atrophy by providing to an animal in need thereof an effective amount of a compound. The compound can modulate the expression levels of multiple mRNA of a muscle atrophy signature. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

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