The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
May. 17, 2017
Applicant:
Nantbio, Inc., Culver City, CA (US);
Inventors:
Shahrooz Rabizadeh, Los Angeles, CA (US);
Kayvan Niazi, Agoura Hills, CA (US);
Oleksandr Buzko, Los Angeles, CA (US);
Justin Golovato, Los Angeles, CA (US);
Patrick Soon-Shiong, Los Angeles, CA (US);
Assignee:
NantBio, Inc., Culver City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 45/06 (2006.01); A61K 31/519 (2006.01); A61K 31/517 (2006.01); A61K 31/506 (2006.01); A61K 31/496 (2006.01); A61K 31/454 (2006.01); A61K 31/435 (2006.01); A61K 31/428 (2006.01); A61K 31/4245 (2006.01); A61K 31/4709 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/428 (2013.01); A61K 31/4245 (2013.01); A61K 31/435 (2013.01); A61K 31/454 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01);
Abstract
The invention relates to a method of modeling K-Ras proteins with one or more mutations that result in constitutive activity, and identifying compounds that inhibit interactions among activated K-Ras proteins and their upstream and downstream effectors.