The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Dec. 10, 2016
Applicant:
Vivolux Ab, Uppsala, SE;
Inventor:
Stig Linder, Bromma, SE;
Assignee:
VIVOLUX AB, Uppsala, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/444 (2006.01); A61P 35/00 (2006.01); A61K 9/19 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/444 (2013.01); A61K 9/19 (2013.01); A61P 35/00 (2018.01); C07D 471/04 (2013.01); A61K 9/0019 (2013.01);
Abstract
The invention provides well-defined and stable pharmaceutical compositions comprising indole derivatives of general formula 1, a process for the preparation of di-hydrochloride salts comprising a high content of the pharmacologically active isomer suitable for industrial production, and use of these in pharmaceutical compositions. The invention further provides a method for use of said compounds for the treatment of cancer. The invention also provides methods to use these compounds in conjunction with other therapies commonly used for treating cancer diseases.