The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Sep. 11, 2018
Applicant:
Horizon Therapeutics, Llc, Lake Forest, IL (US);
Inventors:
Bruce Scharschmidt, San Francisco, CA (US);
Masoud Mokhtarani, Walnut Creek, CA (US);
Assignee:
Horizon Therapeutics, LLC, Lake Forest, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/216 (2006.01); A61K 9/00 (2006.01); G01N 33/84 (2006.01);
U.S. Cl.
CPC ...
A61K 31/216 (2013.01); A61K 9/0053 (2013.01); A61K 9/0095 (2013.01); G01N 33/84 (2013.01); G01N 2800/52 (2013.01); G01N 2800/708 (2013.01);
Abstract
Nitrogen scavenging drugs such as glycerol phenylbutyrate can be administered safely to infants and toddlers with urea cycle disorders by adjusting the dosage based on one or more biomarkers selected from the group consisting of urinary-PAGN and plasma PAA:PAGN ratio.