The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2020

Filed:

Oct. 01, 2013
Applicant:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Inventors:

Stephen J. Blakemore, Littleton, MA (US);

Bin Li, Belmont, MA (US);

Hyunjin Shin, Brookline, MA (US);

William L. Trepicchio, Andover, MA (US);

Assignee:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); C12Q 1/6886 (2018.01); G16B 5/00 (2019.01); C12Q 1/6834 (2018.01); A61K 31/519 (2006.01); G06F 17/18 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 31/519 (2013.01); C12Q 1/6834 (2013.01); G06F 17/18 (2013.01); G16B 5/00 (2019.02); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01);
Abstract

Disclosed herein are markers associated with sensitivity to treatment with therapeutic agents. Methods to identify markers for predicting outcome to treatment with a therapeutic agent are disclosed as well as methods to predict outcome of treatment using markers. Compositions and methods are provided to predict response to NAE inhibition or EGFR inhibition treatment.


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