The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2020

Filed:

Feb. 05, 2018
Applicant:

Manus Bio, Inc., Cambridge, MA (US);

Inventors:

Ajikumar Parayil Kumaran, Watertown, MA (US);

Chin-Giaw Lim, Allston, MA (US);

Souvik Ghosh, Walnut Creek, CA (US);

Christopher Pirie, Seattle, WA (US);

Jason Donald, Lexington, MA (US);

Aaron Love, Boston, MA (US);

Hong Nan, Daly City, CA (US);

Hsien-Chung Tseng, Cambridge, MA (US);

Christine Nicole S. Santos, Newton, MA (US);

Ryan Philippe, Somerville, MA (US);

Assignee:

MANUS BIO INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 5/00 (2006.01); C12N 9/02 (2006.01); C12N 9/04 (2006.01); C12N 9/10 (2006.01); C12P 7/40 (2006.01); C12P 7/26 (2006.01); C12P 7/02 (2006.01); C12P 17/02 (2006.01);
U.S. Cl.
CPC ...
C12P 5/007 (2013.01); C12N 9/0006 (2013.01); C12N 9/0093 (2013.01); C12N 9/1085 (2013.01); C12Y 101/01267 (2013.01); C12Y 117/07001 (2013.01); C12Y 205/0109 (2013.01); C12P 7/02 (2013.01); C12P 7/26 (2013.01); C12P 7/40 (2013.01); C12P 17/02 (2013.01);
Abstract

In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.


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