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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10662441 B1

PDFFull Text
Date of Patent:
May. 26, 2020

Filed:

Jul. 25, 2018

Viral vector targeting cancer stem cells

Applicant:

Kagoshima University, Kagoshima-shi, Kagoshima, JP;

Inventors:

Kenichiro Kosai, Kagoshima, JP;

Yuqing Wang, Kagoshima, JP;

Assignee:

KAGOSHIMA UNIVERSITY, Kagoshima-Shi, JP;

Attorney:

Birch, Stewart, Kolasch & Birch, LLP

Primary Examiner:

Scott Long

Int. Cl.
CPC ...
G01N 33/574 (2006.01); C12N 15/86 (2006.01); C07K 14/705 (2006.01); C12N 15/85 (2006.01); A61K 35/761 (2015.01); A61K 45/06 (2006.01); C12Q 1/6897 (2018.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 35/761 (2013.01); A61K 45/06 (2013.01); C07K 14/70596 (2013.01); C12N 15/85 (2013.01); C12Q 1/6897 (2013.01); G01N 33/574 (2013.01); G01N 33/57492 (2013.01); C12N 2710/10332 (2013.01); C12N 2710/10343 (2013.01); C12N 2830/008 (2013.01);
Abstract

[Problem] To provide a novel and effective method for treating cancer, method for preventing cancer, and method for suppressing metastasis by targeting cancer stem cells, the methods being capable of labeling and damaging cancer stem cells; and to provide a method for damaging and a method for identifying cancer stem cells. [Solution] The present invention provides a viral vector having a promoter that is specifically expressed in cancer stem cells and that can be used for treatment and diagnosis. Furthermore, the present invention provides a method for treating cancer, a method for preventing cancer, and a method for suppressing metastasis using this viral vector, and further provides a method for damaging and a method for identifying cancer stem cells. Furthermore, the present invention provides a labeling agent and a toxic agent for cancer stem cells containing the vector as the active ingredient, and further provides a diagnostic drug, a therapeutic drug, and a metastasis suppressant for cancer.

Find Patent Forward Citations

Kosai, Kenichiro. (2020). Viral vector targeting cancer stem cells (U.S. Patent No. 10662441). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10662441

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