The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2020
Filed:
Jun. 12, 2017
Vaccinex, Inc., Rochester, NY (US);
Ernest S. Smith, W. Henrietta, NY (US);
Tracy Pandina, Rochester, NY (US);
Leslie A. Balch, Lakeville, NY (US);
Mark Paris, Mendon, NY (US);
Maurice Zauderer, Pittsford, NY (US);
Angelica Cornelison, Pittsford, NY (US);
Renee Kirk, Bloomfield, NY (US);
Vaccinex, Inc., Rochester, NY (US);
Abstract
The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eukaryotic cells. The invention further provides methods of selecting and screening for antigen-specific immunoglobulin molecules, and antigen-specific fragments thereof. The invention also provides kits for producing, screening and selecting antigen-specific immunoglobulin molecules. Finally, the invention provides immunoglobulin molecules, and antigen-specific fragments thereof, produced by the methods provided herein.