The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2020

Filed:

Jul. 11, 2017
Applicant:

Leo Pharma A/s, Ballerup, DK;

Inventors:

Alan Stuart Jessiman, Ballerup, DK;

Patrick Stephen Johnson, Ballerup, DK;

Kristoffer Maansson, Ballerup, DK;

Morten Dahl Sørensen, Ballerup, DK;

Assignee:

LEO Pharma A/S, Ballerup, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 241/04 (2006.01);
U.S. Cl.
CPC ...
C07D 413/12 (2013.01); C07D 241/04 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention relates to a compound according to general formula (I) wherein X represents N or CH; Ris —CN, (C-C)alkyl, (C-C)cycloalkyl, (3-7 membered)heterocycloalkyl, (5-6 membered)heteroaryl, (C-C)cycloalkyl(C-C)alkyl, (3-7 membered)heterocycloalkyl-(C-C)alkyl or (5-6 membered)heteroaryl-(C-C)alkyl; Ris halogen, cyano, (C-C)alkyl or (C-C)cycloalkyl; Ris halogen, cyano, (C-C)alkyl, (C-C)haloalkyl or (C-C)cycloalkyl; Ris (C-C)alkyl or (C-C)haloalkyl; Ris (C-C)alkyl, (C-C)cycloalkyl, (C-C)alkyl-(C-C)cycloalkyl, (C-C)cycloalkyl-(C-C)alkyl, (3-7 membered)heterocycloalkyl, phenyl, (5-6 membered)heteroaryl or —OR. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds and to intermediates for preparation of said compounds.


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