The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2020
Filed:
Jul. 28, 2017
Applicant:
Toray Industries, Inc., Tokyo, JP;
Inventors:
Yoshitaka Numajiri, Kanagawa, JP;
Keiichi Okimura, Kanagawa, JP;
Yuki Matsumura, Kanagawa, JP;
Kennunettsu Asaba, Kanagawa, JP;
Tomohide Masuda, Kanagawa, JP;
Kazuyuki Tokumaru, Kanagawa, JP;
Yasufumi Goto, Kanagawa, JP;
Shigeo Fujii, Kanagawa, JP;
Assignee:
Toray Industries, Inc., Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 213/36 (2006.01); C07D 213/57 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 417/12 (2006.01); C07D 213/61 (2006.01); C07D 213/63 (2006.01); C07D 239/26 (2006.01); A61P 37/02 (2006.01); A61P 17/06 (2006.01); A61P 37/08 (2006.01); A61K 31/444 (2006.01); A61K 31/505 (2006.01); A61K 31/4418 (2006.01); C07D 213/84 (2006.01); C07D 213/81 (2006.01); A61P 43/00 (2006.01); A61K 31/4439 (2006.01); A61K 31/443 (2006.01); A61P 37/06 (2006.01); A61K 31/4436 (2006.01);
U.S. Cl.
CPC ...
C07D 213/36 (2013.01); A61K 31/443 (2013.01); A61K 31/444 (2013.01); A61K 31/4418 (2013.01); A61K 31/4436 (2013.01); A61K 31/4439 (2013.01); A61K 31/505 (2013.01); A61P 17/06 (2018.01); A61P 37/02 (2018.01); A61P 37/06 (2018.01); A61P 37/08 (2018.01); A61P 43/00 (2018.01); C07D 213/57 (2013.01); C07D 213/61 (2013.01); C07D 213/63 (2013.01); C07D 213/81 (2013.01); C07D 213/84 (2013.01); C07D 239/26 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 417/12 (2013.01);
Abstract
A compound has a guanidine skeleton that inhibits the protease activity of MALT1 and exerts a therapeutic or prophylactic effect on autoimmune disease such as psoriasis or allergic disease such as atopic dermatitis. The guanidine derivative is typified by the following formula or a pharmacologically acceptable salt thereof.