The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2020
Filed:
Jun. 08, 2017
Applicant:
Hovione Scientia Limited, Cork, IE;
Inventors:
Zita Mendes, Lisbon, PT;
Tiago Fonseca, Loures, PT;
Assignee:
Hovione Scientia Limited, Cork, IE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61P 13/06 (2006.01); A61P 11/06 (2006.01); A61P 11/00 (2006.01); C07D 207/12 (2006.01); C07H 3/04 (2006.01);
U.S. Cl.
CPC ...
C07D 207/12 (2013.01); A61P 11/06 (2018.01); C07H 3/04 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention provides co-crystals of glycopyrronium bromide with lactose. The glycopyrronium bromide and lactose in the novel co-crystals are present in a stoichiometric ratio of from about 1:2 to 2:1. These are characterized by XRD and DSC. Processes for preparing the novel co-crystals are also provided. The co-crystals are also disclosed for use as a medicament, in particular, for treatment of respiratory complaints, such as chronic pulmonary obstructive disease (COPD), bronchitis and asthma. Pharmaceutical compositions comprising the co-crystals as active ingredient are also presented.