The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2020

Filed:

Feb. 08, 2016
Applicant:

Washington State University, Pullman, WA (US);

Inventors:

Amit Bandyopadhyay, Pullman, WA (US);

Susmita Bose, Pullman, WA (US);

Assignee:

Washington State University, Pullman, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B22F 3/105 (2006.01); B22F 3/11 (2006.01); A61F 2/28 (2006.01); B23K 26/342 (2014.01); A61F 2/30 (2006.01); A61F 2/36 (2006.01); A61L 27/42 (2006.01); A61L 27/56 (2006.01); B23K 26/70 (2014.01); A61L 27/06 (2006.01); A61L 27/54 (2006.01); B23K 26/00 (2014.01); B23K 103/14 (2006.01); B23K 103/16 (2006.01); B33Y 10/00 (2015.01); B33Y 50/00 (2015.01); B33Y 70/00 (2020.01); B33Y 80/00 (2015.01);
U.S. Cl.
CPC ...
B23K 26/342 (2015.10); A61F 2/28 (2013.01); A61F 2/30942 (2013.01); A61F 2/36 (2013.01); A61L 27/06 (2013.01); A61L 27/42 (2013.01); A61L 27/427 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); B22F 3/105 (2013.01); B22F 3/1055 (2013.01); B22F 3/1109 (2013.01); B22F 3/1146 (2013.01); B23K 26/0006 (2013.01); B23K 26/70 (2015.10); A61F 2/3094 (2013.01); A61F 2/367 (2013.01); A61F 2/3676 (2013.01); A61F 2002/2817 (2013.01); A61F 2002/30004 (2013.01); A61F 2002/30006 (2013.01); A61F 2002/30011 (2013.01); A61F 2002/30028 (2013.01); A61F 2002/3093 (2013.01); A61F 2002/3097 (2013.01); A61F 2002/30115 (2013.01); A61F 2002/30118 (2013.01); A61F 2002/30179 (2013.01); A61F 2002/30224 (2013.01); A61F 2002/30235 (2013.01); A61F 2002/30322 (2013.01); A61F 2002/30593 (2013.01); A61F 2002/30616 (2013.01); A61F 2002/30677 (2013.01); A61F 2002/30838 (2013.01); A61F 2002/30909 (2013.01); A61F 2230/0006 (2013.01); A61F 2230/0058 (2013.01); A61F 2230/0069 (2013.01); A61F 2250/0014 (2013.01); A61F 2250/0023 (2013.01); A61F 2250/0026 (2013.01); A61F 2310/00017 (2013.01); A61F 2310/00023 (2013.01); A61F 2310/00029 (2013.01); A61F 2310/00047 (2013.01); A61F 2310/00053 (2013.01); A61F 2310/00113 (2013.01); A61F 2310/00155 (2013.01); A61F 2310/00179 (2013.01); A61F 2310/00185 (2013.01); A61F 2310/00227 (2013.01); A61F 2310/00293 (2013.01); A61L 2300/404 (2013.01); A61L 2300/406 (2013.01); A61L 2300/414 (2013.01); A61L 2430/02 (2013.01); B22F 2998/00 (2013.01); B23K 2103/14 (2018.08); B23K 2103/16 (2018.08); B33Y 10/00 (2014.12); B33Y 50/00 (2014.12); B33Y 70/00 (2014.12); B33Y 80/00 (2014.12);
Abstract

Particular aspects provide novel devices for bone tissue engineering, comprising a metal or metal-based composite member/material comprising an interior macroporous structure in which porosity may vary from 0-90% (v), the member comprising a surface region having a surface pore size, porosity, and composition designed to encourage cell growth and adhesion thereon, to provide a device suitable for bone tissue engineering in a recipient subject. In certain aspects, the device further comprises a gradient of pore size, porosity, and material composition extending from the surface region throughout the interior of the device, wherein the gradient transition is continuous, discontinuous or seamless and the growth of cells extending from the surface region inward is promoted.


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