The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2020

Filed:

Aug. 25, 2016
Applicants:

Martin L. Yarmush, Boston, MA (US);

William G. Austen, Weston, MA (US);

Alexander Golberg, Boston, MA (US);

Saiqa L. Khan, Agawam, MA (US);

Inventors:

Martin L. Yarmush, Boston, MA (US);

William G. Austen, Weston, MA (US);

Alexander Golberg, Boston, MA (US);

Saiqa L. Khan, Agawam, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 2/00 (2006.01); B01J 19/08 (2006.01); H05F 3/00 (2006.01); C25B 5/00 (2006.01); A61L 2/03 (2006.01); A61B 18/00 (2006.01); A61B 18/14 (2006.01); C12N 13/00 (2006.01); A61M 25/00 (2006.01); A61N 1/20 (2006.01);
U.S. Cl.
CPC ...
A61L 2/03 (2013.01); A61B 18/00 (2013.01); A61B 18/14 (2013.01); C12N 13/00 (2013.01); A61L 2202/24 (2013.01); A61M 2025/0019 (2013.01); A61N 1/20 (2013.01);
Abstract

A system and method for controlling microbial growth on and in medical devices and implants, especially biofilm infections, involves using pulsed electric fields (PEF). To eradicate at least a portion of a biofilm on a medical implant, for example, 1500 volts can be applied through an electrode system, with pulse duration of 50 μs and pulse delivery frequency of 2 Hz. In the clinical setting, systemic microbial therapy can be combined with PEF to achieve a synergistic effect leading to improved eradication of infections.


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