The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2020
Filed:
Mar. 05, 2014
Applicant:
Hanmi Pharm. Co., Ltd., Hwaseong-si, Gyeonggi-do, KR;
Inventors:
Myung Hyun Jang, Seoul, KR;
Min Young Kim, Suwon-si, KR;
Dae Jin Kim, Hwaseong-si, KR;
Sung Youb Jung, Yongin-si, KR;
Se Chang Kwon, Seoul, KR;
Assignee:
HANMI PHARM. CO., LTD, Hwaseong-si, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); G01N 33/53 (2006.01); A61K 38/28 (2006.01); C07K 1/107 (2006.01); C07K 14/62 (2006.01);
U.S. Cl.
CPC ...
A61K 38/28 (2013.01); A61K 47/68 (2017.08); A61K 47/6811 (2017.08); C07K 1/1077 (2013.01); C07K 14/62 (2013.01); C07K 2319/30 (2013.01);
Abstract
A method for preparing a conjugate by linking a physiologically active polypeptide, a non-peptidyl polymer linker, and an immunoglobulin constant region via a covalent bond are disclosed. The method enables an efficient preparation of a physiologically active polypeptide conjugate, in which a salt is used in a coupling reaction to improve the problem of low production yield during preparation of the physiologically active polypeptide conjugate.