The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2020
Filed:
Nov. 02, 2016
Applicant:
University of Rochester, Rochester, NY (US);
Inventors:
Robert Boeckman, Honeye Falls, NY (US);
Brendan Boyce, Woodbury, NY (US);
Lifeng Xiao, Rochester, NY (US);
Zhenqiang Yao, Pittsford, NY (US);
Frank H. Ebetino, Venice, FL (US);
Assignee:
University of Rochester, Rochester, NY (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/60 (2006.01); A61K 31/4706 (2006.01); A61K 47/54 (2017.01);
U.S. Cl.
CPC ...
A61K 31/4706 (2013.01); A61K 47/548 (2017.08); C07F 9/60 (2013.01);
Abstract
The present invention provides compositions and methods for providing controllable local delivery of a conjugate of chloroquine (CQ) and a bisphosphonate to treat diseases characterized by abnormal bone metabolism. In certain embodiments, the invention is used as a treatment for a subject with diseases and disorders characterized by bone loss.