The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2020

Filed:

Aug. 07, 2018
Applicant:

Old Dominion University Research Foundation, Norfolk, VA (US);

Inventors:

Karl H. Schoenbach, Norfolk, VA (US);

Richard Heller, Norfolk, VA (US);

James Camp, King George, VA (US);

Stephen P. Beebe, Norfolk, VA (US);

Shu Xiao, Norfolk, VA (US);

Amy Donate, Yorktown, VA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 18/12 (2006.01); A61N 1/40 (2006.01); A61N 1/32 (2006.01); A61N 5/00 (2006.01); A61N 5/02 (2006.01); A61N 5/06 (2006.01); A61B 18/18 (2006.01); A61B 18/20 (2006.01); A61B 18/00 (2006.01); A61N 5/067 (2006.01); A61B 18/24 (2006.01);
U.S. Cl.
CPC ...
A61B 18/1206 (2013.01); A61B 18/12 (2013.01); A61N 1/327 (2013.01); A61N 1/403 (2013.01); A61N 5/00 (2013.01); A61N 5/025 (2013.01); A61N 5/0625 (2013.01); A61B 18/1815 (2013.01); A61B 18/20 (2013.01); A61B 18/24 (2013.01); A61B 2018/00613 (2013.01); A61B 2018/00761 (2013.01); A61B 2018/00767 (2013.01); A61B 2018/00791 (2013.01); A61B 2018/00994 (2013.01); A61N 2005/067 (2013.01); A61N 2005/0651 (2013.01); A61N 2005/0666 (2013.01);
Abstract

Systems and methods for treatment of a biological tissues including target tissues and other tissues. The method includes elevating a temperature of the target tissues above a physiological temperature of the biological tissues to treatment temperature, and generating an electric field extending through at least a portion of the target tissues using a pre-defined sequence of short voltage pulses applied between at least two electrodes. In the method, the treatment temperature is maintained during the generating. Further, the pre-defined sequence is selected such that a magnitude of the electric field generated is sufficient to induce electromanipulation in the portion of the target tissues without substantially elevating of the temperature of the portion of the target tissues above the treatment temperature.


Find Patent Forward Citations

Loading…