The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2020

Filed:

Oct. 20, 2015
Applicant:

Melaleuca, Inc., Idaho Falls, ID (US);

Inventors:

Alexander B. Rabovsky, Idaho Falls, ID (US);

Bruno Fink, Elzach, DE;

Assignee:

Melaleuca, Inc., Idaho Falls, ID (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 33/84 (2006.01); G01N 33/48 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5044 (2013.01); G01N 33/48 (2013.01); G01N 33/5032 (2013.01); G01N 33/84 (2013.01);
Abstract

Provided herein are methods and materials for assessing platelet activity and/or the ability of substances (e.g., small molecule compounds and compositions comprising the same) to inhibit or activate platelet activity. For example, this document provides methods and materials that can include (a) applying abnormal flow conditions (e.g., oscillatory shear stress) to a sample of platelets (e.g., a blood sample or platelet-rich plasma sample) to stimulate the platelets, and (b) assessing the activity of the platelets. In some embodiments, the activity of the platelets can be assessed by measuring the amount of superoxide radial or the rate and/or level of platelet aggregation within the sample.


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