The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
May. 24, 2017
Applicant:
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Inventors:
Dmitriy Gremyachinskiy, San Francisco, CA (US);
Meng Taing, Hayward, CA (US);
Aruna Ayer, Santa Clara, CA (US);
Peter J. Crisalli, Mountain View, CA (US);
Assignee:
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C07H 19/10 (2006.01); C12Q 1/6874 (2018.01); G01N 27/447 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C07H 19/10 (2013.01); G01N 27/44791 (2013.01); G01N 33/48721 (2013.01);
Abstract
The present disclosure relates to tagged multi-nucleotide compounds, which comprise a single tag moiety covalently linked to a plurality of nucleoside-5'-oligophosphate moieties. As disclosed herein, these tagged multi-nucleotide compounds have improved characteristics as polymerase substrates and can be used in a range of nucleic acid detection and sequencing methods, including nanopore sequencing-by-synthesis.