The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Dec. 21, 2018
Applicant:
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Inventors:
Satwik Kamtekar, Mountain View, CA (US);
Lubomir Sebo, Hayward, CA (US);
Leewin Chern, Fremont, CA (US);
Thomas Linsky, Mountain View, CA (US);
Jeremiah Hanes, Woodside, CA (US);
Erik Miller, Berkeley, CA (US);
Ying Yang, Fremont, CA (US);
Stephen Yue, Eugene, OR (US);
Assignee:
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6848 (2018.01); C12N 9/22 (2006.01); C07K 14/36 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6848 (2013.01); C07K 14/36 (2013.01); C12N 9/22 (2013.01);
Abstract
Compositions comprising covalently modified and mutated biotin-binding proteins, particularly biotin-binding proteins having a negative charge at physiological pH, are provided. Methods of producing such proteins are also provided, as are methods of immobilizing, sequencing, and making nucleic acids employing such proteins.