The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2020

Filed:

Mar. 04, 2019
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Ralph Weissleder, West Peabody, MA (US);

Sarit S. Agasti, Brighton, MA (US);

Vanessa M. Peterson, Somerville, MA (US);

Adeeti Ullal, Saratoga, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6804 (2018.01); C12Q 1/6816 (2018.01); C12Q 1/6823 (2018.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6804 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6823 (2013.01); G01N 33/53 (2013.01); G01N 2458/10 (2013.01);
Abstract

Described herein are methods, compositions, kits and systems for multiplexed detection of target molecules from a sample. In some embodiments, the methods, compositions, kits and systems can be used to perform multiplexed protein analysis of a sample (e.g., a sample comprising a small number of cells or a single-cell sample). In some embodiments, the same sample subjected to a multiplexed protein analysis using the methods, compositions, kits and systems described herein can also be subjected to a nucleic acid (e.g., RNAs, microRNAs, and/or DNA) analysis, thereby creating an integrated expression profiling from a limited amount of sample.


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