The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Jul. 26, 2016
Applicants:
Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;
Universite Paris-sud, Orsay, FR;
Inventors:
Olivier Christophe, Le Kremlin-bicetre, FR;
Cecile Denis, Le Kremlin-bicetre, FR;
Peter Lenting, Le Kremlin-bicetre, FR;
Assignees:
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), Paris, FR;
UNIVERSITE PARIS—SUD, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 13/00 (2006.01); C12N 9/64 (2006.01); A61P 7/04 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/6432 (2013.01); A61P 7/04 (2018.01); C12Y 304/21006 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention relates to mutated factor (FX) polypeptides and uses thereof for the treatment of haemophilia. In particular, the present invention relates to a mutated factor X (FX) polypeptide which comprises a heavy chain wherein at least one amino acid residue at position 441 and/or 448 of SEQ ID NO: 1 is mutated.