The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Jan. 27, 2016
Emory University, Atlanta, GA (US);
Georgia Tech Research Corporation, Atlanta, GA (US);
H. Trent Spencer, Marietta, GA (US);
Christopher Doering, Atlanta, GA (US);
Philip M. Zakas, Atlanta, GA (US);
Eric Gaucher, Atlanta, GA (US);
Emory University, Atlanta, GA (US);
Georgia Tech Research Corporation, Atlanta, GA (US);
Abstract
This disclosure relates to recombinant or chimeric FVIII proteins, variants, and vectors encoding the proteins containing one or more ancestral mutations. In certain embodiments, one or more protein domains comprise amino acid sequences that are derived from ancestrally reconstructed amino acid sequences. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising the proteins or vectors and related methods of inducing blood clotting.