The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Jan. 28, 2015
Applicant:
University Health Network, Toronto, CA;
Inventors:
Assignee:
University Health Network, Toronto, CA;
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/725 (2006.01); C12N 15/10 (2006.01); C12N 5/078 (2010.01);
U.S. Cl.
CPC ...
C07K 14/7051 (2013.01); C12N 5/0634 (2013.01); C12N 15/1034 (2013.01); C12N 15/1055 (2013.01); C12N 15/1037 (2013.01); C12N 2510/00 (2013.01);
Abstract
Provided is a method for determining a TCR polypeptide chain that can form a TCR specific for a peptide of interest. Also provided are methods and compositions for producing a cell expressing a T cell receptor (TCR) specific for a peptide of interest, methods and compositions for producing a TCR chain nucleic acid and/or pair of TCR chain polypeptides and/or nucleic acids encoding a TCR, a cell population comprising the cell harboring the nucleic acids encoding a TCR obtained by said method, and a method for treating a disorder comprising administering to the subject said cell population.