The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Nov. 16, 2018
Applicant:
Molecular Templates, Inc., Austin, TX (US);
Inventors:
Jian-Xin Duan, South San Francisco, CA (US);
Mark Matteucci, Portola Valley, CA (US);
Nipun Davar, Pleasanton, CA (US);
Denise Andersen, Montara, CA (US);
Assignee:
Molecular Templates, Inc., Austin, TX (US);
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/6506 (2006.01); A61K 31/661 (2006.01); A61K 31/664 (2006.01); A61K 45/06 (2006.01); A61K 31/675 (2006.01);
U.S. Cl.
CPC ...
C07F 9/6506 (2013.01); A61K 31/664 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention provides a new method for making TH-302 and solid forms thereof. The compound in its solid form is an effective anti-cancer agent and may be used in various pharmaceutical compositions, and are particularly effective for the treatment of cancer. The invention also provides a method for preparing such compounds and forms and for treating cancer in a mammal comprising the step of administering a therapeutically effective amount of a solid form of TH-302 thereof.