The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2020

Filed:

Sep. 18, 2017
Applicant:

Nanjing Chuangte Pharmaceutical Technology Co., Ltd, Nanjing, CN;

Inventors:

Yongqiang Zhu, Nanjing, CN;

Zhaogang Liu, Nanjing, CN;

Chao Feng, Nanjing, CN;

Shihe Hu, Nanjing, CN;

Hao Chen, Nanjing, CN;

Enhe Bai, Nanjing, CN;

Jie Wang, Nanjing, CN;

Jingmiao Shi, Nanjing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/06 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61K 31/506 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/06 (2013.01); A61K 31/506 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C07B 59/002 (2013.01); C07B 2200/05 (2013.01);
Abstract

A type of deuterated 3-(4,5-substituted aminopyrimidine)phenyl derivatives and use thereof. The derivatives are compounds of Formula (I) or pharmaceutically acceptable salts thereof. These compounds or salts thereof can be used for treatment or prevention of diseases or illnesses through certain mutant forms of epidermal growth factor receptors, inhibit the growth of various tumor cells effectively, and inhibit other proteases of EGFR and Her families, they can be used for preparing anti-tumor drugs.


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