logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10654837 B1

PDFFull Text
Expired
Date of Patent:
May. 19, 2020

Filed:

Feb. 06, 2018

Sulphamoylaryl derivatives and use thereof as medicaments for the treatment of liver fibrosis

Applicant:

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

Zhao-Kui Wan, Shanghai, CN;

Haibing Guo, Shanghai, CN;

Koen Vandyck, Paal-Beringen, BE;

Pierre Jean-Marie Bernard Raboisson, Wavre, BE;

Abdellah Tahri, Beerse, BE;

Assignee:

Janssen Pharmaceutica NV, Beerse, BE;

Attorney:
Primary Examiner:

Kristin A Vajda

Int. Cl.
CPC ...
C07D 405/12 (2006.01); C07D 401/12 (2006.01); C07D 211/58 (2006.01); C07D 307/22 (2006.01); C07D 305/04 (2006.01); C07D 417/12 (2006.01); C07D 213/75 (2006.01); C07D 309/14 (2006.01); C07C 311/16 (2006.01); C07C 311/29 (2006.01); A61P 1/16 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); A61P 1/16 (2018.01); C07C 311/16 (2013.01); C07C 311/29 (2013.01); C07D 211/58 (2013.01); C07D 213/75 (2013.01); C07D 305/04 (2013.01); C07D 307/22 (2013.01); C07D 309/14 (2013.01); C07D 401/12 (2013.01); C07D 417/12 (2013.01); A61K 45/06 (2013.01); C07B 2200/05 (2013.01);
Abstract

Potent 5-HT2B antagonist of Formula (A), including stereochemically isomeric forms, and salts, hydrates, solvates thereof and their use wherein R1 to R4 and Ar have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them, alone or in combination with other drugs, in fibrosis and/or cirrhosis prevention or therapy.

Find Patent Forward Citations

Wan, Zhao-Kui. (2020). Sulphamoylaryl derivatives and use thereof as medicaments for the treatment of liver fibrosis (U.S. Patent No. 10654837). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10654837

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…