The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2020

Filed:

Feb. 19, 2017
Applicant:

Zhejiang Jingxin Pharmaceutical Co., Ltd., Xinchang County, Zhejiang Province, CN;

Inventors:

Jianrong Zhu, Xinchang County, CN;

Chunyong Peng, Xinchang County, CN;

Hongban Zhong, Xinchang County, CN;

Xiurong Hu, Xinchang County, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/79 (2006.01); A61K 31/343 (2006.01); B01D 9/00 (2006.01); A61P 25/20 (2006.01);
U.S. Cl.
CPC ...
C07D 307/79 (2013.01); A61K 31/343 (2013.01); B01D 9/0004 (2013.01); B01D 9/005 (2013.01); A61P 25/20 (2018.01);
Abstract

Crystal forms I and II of tasimelteon. Crystal form I: an X-ray powder diffraction spectrum using CuKα radiation and represented by a 2θ angle has diffraction peaks at least at 7.2°±0.2°, 7.9°±0.2°, 10.6°±0.2°, 14.4°±0.2°, 15.9°±0.2°, 17.3°±0.2°, 21.0°±0.2°, 23.2°±0.2°, and 24.4°±0.2°. Crystal form II: an X-ray powder diffraction spectrum using CuKα radiation and represented by a 2θ angle has diffraction peaks at least at 6.8°±0.2°, 12.1°±0.2°, 12.5°±0.2°, 13.1°±0.2°, 13.6°±0.2°, 13.8°±0.2°, 15.8°±0.2°, 17.0°±0.2°, 18.4°±0.2°, 20.8°±0.2°, 24.2°±0.2°, and 24.4°±0.2°. Crystal forms I and II of tasimelteon have advantages of excellent physicochemical property, good stability and solubility, and simple operation for preparation.


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