The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2020

Filed:

Dec. 27, 2017
Applicant:

Shenzhen Chipscreen Biosciences Co., Ltd., Shenzhen, Guangdong, CN;

Inventors:

Qianjiao Yang, Guangdong, CN;

Xianping Lu, Guangdong, CN;

Zhibin Li, Guangdong, CN;

Lijun Xin, Guangdong, CN;

Yonglian Song, Guangdong, CN;

Chao Fu, Guangdong, CN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 265/30 (2006.01); C07C 275/24 (2006.01); C07D 405/12 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 265/30 (2013.01); C07C 275/24 (2013.01); C07D 405/12 (2013.01); C07D 413/14 (2013.01);
Abstract

The present invention relates to a urea compound and a preparation method and an application thereof. The structure of the present compound is represented by formula (I), the definition of each variable in the formula being as described in the description. The compound can block interaction between the PD-1/PD-L1 signalling pathways. The compound of the present invention can be used for treating or preventing diseases related to the signalling pathways, such as cancer, autoimmune disease, chronic infectious disease, and other diseases.


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