The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Nov. 21, 2016
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Joseph Wang, San Diego, CA (US);
Liangfang Zhang, San Diego, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2020.01); A61K 49/00 (2006.01); A61K 35/18 (2015.01); A61K 9/50 (2006.01); A61K 47/69 (2017.01); A61K 9/51 (2006.01); A61K 9/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 49/0097 (2013.01); A61K 9/0009 (2013.01); A61K 9/5094 (2013.01); A61K 9/5115 (2013.01); A61K 35/18 (2013.01); A61K 41/00 (2013.01); A61K 47/6901 (2017.08); A61K 49/0067 (2013.01); A61K 2035/124 (2013.01);
Abstract
Living cells, such as red blood cells (RBCs) modified with functional micromotors with the aid of ultrasound propulsion and magnetic guidance. Iron oxide nanoparticles are loaded into the RBCs, where their asymmetric distribution within the cells results in a net magnetization, thus enabling magnetic alignment and guidance under acoustic propulsion. The RBC motors display efficient guided and prolonged propulsion in various biological fluids, including undiluted whole blood.