The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Feb. 10, 2017
Applicants:
University of Iowa Research Foundation, Iowa City, IA (US);
Integrated Dna Technologies, Inc., Coralville, IA (US);
Inventors:
James O. McNamara, II, Iowa City, IA (US);
Katie R. Flenker, Iowa City, IA (US);
Lingyan Huang, Coralville, IA (US);
Alexander R. Horswill, Iowa City, IA (US);
Mark A. Behlke, Coralville, IA (US);
Frank J. Hernandez, Iowa City, IA (US);
Assignees:
University of Iowa Research Foundation, Iowa City, IA (US);
Integrated DNA Technologies, Inc., Coralville, IA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C07H 21/00 (2006.01); C12P 19/34 (2006.01); A61K 49/00 (2006.01); G01N 33/569 (2006.01); C12Q 1/44 (2006.01); G01N 33/542 (2006.01); C12Q 1/689 (2018.01); C12Q 1/6818 (2018.01); C12Q 1/6823 (2018.01);
U.S. Cl.
CPC ...
A61K 49/0054 (2013.01); A61K 49/0052 (2013.01); C12Q 1/44 (2013.01); C12Q 1/689 (2013.01); C12Q 1/6818 (2013.01); C12Q 1/6823 (2013.01); G01N 33/542 (2013.01); G01N 33/569 (2013.01); G01N 2333/922 (2013.01);
Abstract
The present invention relates to a rapid detection of microbial-associated nuclease activity with chemically modified nuclease (e.g., ribonuclease) substrates, and probes and compositions useful in detection assays.