The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2020

Filed:

Nov. 09, 2017
Applicant:

Colorado School of Mines, Golden, CO (US);

Inventors:

Melissa D. Krebs, Englewood, CO (US);

Gulsu Sener Yildirim, Boulder, CO (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/32 (2006.01); C08F 120/38 (2006.01); C08J 9/00 (2006.01); A61K 9/06 (2006.01); A61K 38/16 (2006.01); C08F 220/38 (2006.01);
U.S. Cl.
CPC ...
A61K 47/32 (2013.01); A61K 9/06 (2013.01); A61K 38/16 (2013.01); C08F 120/38 (2013.01); C08F 220/38 (2013.01); C08J 9/0061 (2013.01); C08J 2201/026 (2013.01); C08J 2205/022 (2013.01); C08J 2205/044 (2013.01); C08J 2205/05 (2013.01); C08J 2207/10 (2013.01); C08J 2333/14 (2013.01);
Abstract

Methods of producing microporous zwitterionic cryogels are described, wherein the cryogels are useful for sustaining release of therapeutic agents. The disclosed cryogels overcome several limitations associated with existing compositions, for example the disclosed cryogels have high loading efficiencies and a sustained release profile with minimal burst of up to 4 months or more. The characteristics of the disclosed cryogels can be varied by altering monomer (e.g. zwitterion) and crosslinker selection. The amount of monomer contained in the hydrogel may also be varied to aid in controlling the cryogel's chemistry.


Find Patent Forward Citations

Loading…